Search Results (303)

Interdisciplinary and integrated powerful knowledge (IIPK) is the outcome of integrating multiple disciplinary perspectives and approaches to tackle challenging real-world issues. Using many disciplinary fields, IIPK is essential for problem solving, innovation, and technical breakthroughs that require careful, imaginative, and innovative application of a wide range of disciplinary knowledge. It is especially relevant when addressing socio-scientific issues, which require a comprehensive understanding of scientific, social, and ethical dimensions. Collaborative and interdisciplinary work among people with diverse backgrounds and expertise is necessary to advance IIPK, including professionals from different academic fields, policymakers, stakeholders, and community members who bring various perspectives and values to the table. The co-creation of IIPK could inform policy making, support informed decision making, and lead to more comprehensive, effective, and sustainable solutions. Theoretical underpinnings and practical applications of co-creating IIPK are discussed here based on several principles with the potential to impact current practices. The co-creation and dissemination of IIPK could use multiple platforms, such as scholarly articles, encyclopedias, and media, including social media. These platforms provide scope for co-creating powerful knowledge through a people participatory approach, which would lead to changes in practices. Full article

This entry discusses the importance of cultural competence in the healthcare of humans and animals, its challenges, its mixed research results, and the need for widely applicable competencies. Although there is research evidence showing that cultural competence is linked with patient satisfaction, better doctor–patient relationships, adherence to therapy, and to some extent, better health outcomes, there is a huge variety of models and competencies in the literature, which has sometimes resulted in inclusive outcomes, confusion as to what constitutes the necessary competencies, and patchy implementation. In spite of the development of cultural competence in human healthcare, its implementation in veterinary medicine remains poor. On this note, the aims of this entry are to provide a brief overview of the cultural competence in healthcare and veterinary medicine and education, to outline the important facts, and to highlight the need for more standardisation in implementing and testing widely applicable cultural competencies for both human and veterinary healthcare. Full article

The domestication of humans is not an issue of domesticity but of the effects of the domestication syndrome on a hominin species and its genome. These effects are well expressed in the ‘anatomically modern humans’, in their physiology, behavior, genetic defects, neuropathology, and distinctive neoteny. The physiological differences between modern (gracile) humans and their ancestors, robust Homo sapiens types, are all accounted for by the domestication syndrome. From deductions we can draw about early human behavior, it appears that modifications are attributable to the same cause. The domestication hypothesis ascribes the initiation of the changes to selective breeding introduced by the consistent selection of neotenous features. That would trigger genetic pleiotropy, causing the changes that are observed. Full article

Feedback is essential for the development of veterinary medical learners. This review explores the theory and practical use of feedback in the modern clinical teaching environment. Our purpose is to assist veterinary teaching institutions engage in effective feedback exchange between instructors and learners. Based on literature evidence, quality feedback requires training for both learners and instructors. Effectively executed feedback should be a powerful learning and teaching tool in the development of competencies of the learner. Following the theoretical discussion, we propose a method for delivering scheduled feedback sessions to veterinary medical learners. This differs from ‘on-the-go’ feedback during each clinical encounter, which we have discussed in a previous article related to the use of the five microskills in clinical teaching. Full article

Achieving optimal treatment outcomes in glaucoma requires patients to adhere to their medication regimens. Possible barriers to patients’ cooperation include the misunderstanding of a treatment’s importance or errors in applying instructions, forgetfulness, financial constraints and others. Due to the fact that glaucoma usually causes no apparent symptoms or pain, on the one hand, and the significant inconvenience that the eye drops used for glaucoma treatment can cause due to local irritation, on the other, patient compliance is a challenge. To address this challenge, we require strategies for improving adherence to glaucoma treatment. The importance of proper eye drop administration techniques cannot be overstated, particularly for vulnerable populations such as the elderly, the sick and the visually handicapped. Studies have shown that failure to comply with glaucoma treatment is a significant factor affecting disease progression, emphasizing the need for interventions that improve patient compliance. Educational interventions, medication reminders and the use of assistive devices such as eye drop aids have been shown to improve adherence to glaucoma treatment. By promoting strategies that can be used to enhance treatment adherence, healthcare providers can ensure that glaucoma patients receive the full benefits of their treatment plans, reducing the risk of disease progression. Many patients struggle with the complexity of their treatment regimens and the challenges of administering eye drops. This entry provides a comprehensive overview of the different barriers to patient adherence to glaucoma eye drop treatment, emphasizing the difficulties associated with eye drop instillation. This entry examines a range of eye drop aids available to patients, evaluating their modes of action, benefits, drawbacks and effectiveness in improving patient compliance. By providing detailed information on the barriers to adherence and the range of eye drop aids available, this entry aims to support healthcare providers in helping glaucoma patients to achieve better treatment adherence and outcomes. Full article

Fungi constitute a diverse group with highly positive and negative impacts in different environments, having several natural roles and beneficial applications in human life, but also causing several concerns. Fungi can affect human health directly, but also indirectly by being detrimental for animal and plant health, influencing food safety and security. Climate changes are also affecting fungal distribution, prevalence, and their impact on different settings. Searching for sustainable solutions to deal with these issues is challenging due to the complex interactions among fungi and agricultural and forestry plants, animal production, environment, and human and animal health. In this way, the “One Health” approach may be useful to obtain some answers since it recognizes that human health is closely connected to animal and plant health, as well as to the shared environment. This review aims to explore and correlate each of those factors influencing human health in this “One Health” perspective. Thus, the impact of fungi on plants, human, and animal health, and the role of the environment as an influencing factor on these elements are discussed. Full article

To determine whether (or not) the intrinsic predictability limit of the atmosphere is two weeks and whether (or not) Lorenz’s approaches support this limit, this entry discusses the following topics: (A). The Lorenz 1963 model qualitatively revealed the essence of a finite predictability within a chaotic system such as the atmosphere. However, the Lorenz 1963 model did not determine a precise limit for atmospheric predictability. (B). In the 1960s, using real-world models, the two-week predictability limit was originally estimated based on a doubling time of five days. The finding was documented by Charney et al. in 1966 and has become a consensus. Throughout this entry, Major Point A and B are used as respective references for these topics. A literature review and an analysis suggested that the Lorenz 1963 model qualitatively revealed a finite predictability, and that findings of the Lorenz 1969 model with a saturation assumption supported the idea of the two-week predictability limit, which, in the 1960s, was estimated based on a doubling time of five days obtained using real-world models. However, the theoretical Lorenz 1963 and 1969 models have limitations, such as a lack of certain processes and assumptions, and, therefore, cannot represent an intrinsic predictability limit of the atmosphere. This entry suggests an optimistic view for searching for a predictability limit using different approaches and is supported by recent promising simulations that go beyond two weeks. Full article

Almost half of the world’s countries, including cities, have strategically adopted the territorial brand. This essay proposes an interdisciplinary reflection on the relationship between territorial brands and territorial and regional development theories. It discusses how the brand relates to the territory, making it a social actor mediated by a distinctive signal, the territorial brand. The intersection between the concepts of territory and brand reveals the legitimation strategies of social actors in producing a collective space delimited by power relations. Beyond the economic and tourist spheres, this context brings new debates to politics, theory, and social sciences in interdisciplinary regional development. Full article

In the 21st century, prior to the outbreak of the COVID-19 pandemic, numerous transformations were already underway in the field of employment. However, this unprecedented global health crisis has had a profound influence on employment worldwide, yielding both positive and negative outcomes across various labor aspects. Consequently, while certain effects are anticipated to be temporary, others are likely to instigate enduring changes in employment practices. Full article

Climate change is a shift in the climate’s condition that lasts for an extended period, usually decades or longer, and that may be detected by changes in the mean and variability of its parameters. The full spectrum of players and their related value-adding activities, that are a part of the food supply chain, including the disposal of food items derived from agriculture, forestry, or fisheries, are collectively called food systems. Food systems are a component of their larger economic, social, and environmental contexts. Finally, food security is the condition in which all individuals consistently have physical and financial access to adequate safe, nutritious food that satisfies their dietary needs and food choices for an active and healthy life. Climate change and its relationships with food systems and security are complex since food systems significantly contribute to climate change. However, climate change impacts food systems unpredictably, leading to food insecurity through adverse impacts on the four dimensions of food security: utilization, access, food availability, and stability. Climate change adaptation plans are urgent and include measures such as flood and climate protection, waste management and recycling, climate-smart agriculture, and analytical climatic conditions innovation equipment on agricultural processes and activities. Nevertheless, addressing the climate crisis and its adverse impacts on food security through the activation and promotion of innovation needs reliable information and intervention in many different but interconnected fields, such as institutional design, philanthropy, novel partnerships, finance, and international cooperation. In this context, this paper analyses the relationship between climate change, agriculture, and global–local strategies to ensure food security and also discusses policies’ role in fostering innovation for supporting local agro-food systems and their capacity to sustain societal needs. Full article

Integrated optics is a field of study and technology that focuses on the design, fabrication, and application of optical devices and systems using integrated circuit technology. It involves the integration of various optical components, such as waveguides, couplers, modulators, detectors, and lasers, into a single substrate. One of the key advantages of integrated optics is its compatibility with electronic integrated circuits. This compatibility enables seamless integration of optical and electronic functionalities onto the same chip, allowing efficient data transfer between optical and electronic domains. This synergy is crucial for applications such as optical interconnects in high-speed communication systems, optical sensing interfaces, and optoelectronic integrated circuits. This entry presents a brief study on some of the widely used and commercially available optical platforms and fabrication methods that can be used to create photonic integrated circuits. Full article

Flash radiotherapy (Flash-RT) is an innovative technique used in radiotherapy for cancer treatment because it delivers an extremely high dose of radiation (>40 Gy/s) to the tumour in a very short period of time, typically within a fraction of a second. This ultra-fast delivery of radiation distinguishes Flash-RT from conventional radiotherapy, which typically involves the delivery of radiation over a longer time period, often several minutes. Studies conducted in cell and preclinical models suggested that Flash-RT may spare normal tissues from radiation-related side effects, such as skin toxicity, gastrointestinal complications, and damage to organs-at-risk. This is believed to be due to the unique normal tissue response to the ultra-high dose rate. Nevertheless, while Flash-RT shows promising results in preclinical and early clinical studies, one should note that the technique is still in the early stages of development. This entry provides a comprehensive exploration of the immense potentials of Flash-RT, covering its background, mechanisms, radiation sources, recent experimental findings based on cell and preclinical models, and future prospects. It aims to provide valuable insights into this innovative radiotherapy technology for anyone interested in the subject. Full article

Interest in covalent organic frameworks as high-value materials has grown steadily since their development in the 2000s. However, the great advantage that allows us to obtain these crystalline materials—the reversibility of the bonds that form the network—supposes a drawback in terms of thermal and chemical stability. Among the different strategies employed for the stabilization of imine-based Covalent Organic Frameworks (COFs), cycloaddition and other related cyclization reactions are especially significant to obtain highly stable networks with extended π-delocalization and new functionalities, expanding even further the potential application of these materials. Therefore, this entry gathered the most recent research strategies for obtaining stable COFs by means of cyclization reactions, including the Povarov reaction and intramolecular oxidative cyclization reactions as well as some other recent innovative approaches. Full article

Nature is composed of elements at various spatial scales, ranging from the atomic to the astronomical level. In general, human sensory experience is limited to the mid-range of these spatial scales, in that the scales which represent the world of the very small or very large are generally apart from our sensory experiences. Furthermore, the complexities of Nature and its underlying elements are not tractable nor easily recognized by the traditional forms of human reasoning. Instead, the natural and mathematical sciences have emerged to model the complexities of Nature, leading to knowledge of the physical world. This level of predictiveness far exceeds any mere visual representations as naively formed in the Mind. In particular, geometry has served an outsized role in the mathematical representations of Nature, such as in the explanation of the movement of planets across the night sky. Geometry not only provides a framework for knowledge of the myriad of natural processes, but also as a mechanism for the theoretical understanding of those natural processes not yet observed, leading to visualization, abstraction, and models with insight and explanatory power. Without these tools, human experience would be limited to sensory feedback, which reflects a very small fraction of the properties of objects that exist in the natural world. As a consequence, as taught during the times of antiquity, geometry is essential for forming knowledge and differentiating opinion from true belief. It not only provides a framework for understanding astronomy, classical mechanics, and relativistic physics, but also the morphological evolution of living organisms, along with the complexities of the cognitive systems. Geometry also has a role in the information sciences, where it has explanatory power in visualizing the flow, structure, and organization of information in a system. This role further impacts the explanations of the internals of deep learning systems as developed in the fields of computer science and engineering. Full article

There has been renewed interest in the application of endophytic fungi to control phytopathogenic fungi, which cause significant damage to crop health, ultimately leading to losses in agricultural productivity. Endophytic fungi inhibit pathogens via different modes of action—mycoparasitism, competition (for nutrients and ecological niches), antibiosis, and induction of plant defense—thus demonstrating the ability to control a wide range of phytopathogenic fungi in different growth phases and habitats. However, many studies have been conducted under laboratory conditions, and there is a huge lack of studies in which real field testing was performed. Aspergillus, Clonostachys, Coniothyrium, Trichoderma, and Verticillium have been proven to be the most effective fungal biocontrol agents. Trichoderma is regarded as the most promising group in commercial formulations. In this study, we attempted to emphasize the significance of fungal endophytes in controlling phytopathogenic fungi, while reporting recent advances in endophytic biology and application. Full article